Some people find how they self-control HIV

2024/04/24 Etxebeste Aduriz, Egoitz - Elhuyar Zientzia Iturria: Elhuyar aldizkaria

• Osasuna
• Medikuntza
• Mikrobiologia

People with intrinsic HIV control capabilities find how they get it. Researchers see the possibility of creating immunotherapy that mimics this mechanism for patients to control the virus in the same way. The paper has been published in the journal The Journal of Clinical Investigation.

Some people are able to control HIV. These include those who lose control of the virus upon reaching a point and those who keep it under indefinite control. Differences between them have been studied by ultrasonic techniques capable of detecting viruses (virus deposition) hidden in the genome.

And you've seen that those who lose control of the virus, although very few viruses are complete, have the integrated cell machinery in the genome fields they have access to. This allows you to create new viruses. For those who keep unlimited virus under control, viruses are integrated into so-called gene deserts. And in these cases, they could never generate new contaminating viruses.

According to the researchers, this study has opened the doors to further study the mechanisms of virus exclusion in these areas. The goal is to find targets for the development of immunotherapy, so that most people with HIV manage to control the virus, as do those who spontaneously manage it.